The oral fluid or saliva drugs of abuse laboratory test confirmation has shown accuracy similar to urine tests in clinical trials, according to the manufacturer; confirmation testing can also be performed from oral fluid.
It is important change will allow the testing of specimens other than urine. Proposed additional specimens include oral fluids, sweat, and hair. Caplan noted that the use of oral fluids avoids some of the problems associated with use of urine specimens. Oral fluids can be collected immediately and under direct observation. He stated that privacy issues cause urine collection to be monitored, but the actual collection is not observed. For this reason, there are always concerns about contamination, adulteration, or substitution.